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RNAi for contactin 2 inhibits proliferation of U87-glioma stem cells by downregulating AICD, EGFR, and HES1

Glioblastoma is the most common form of malignant brain tumors and has a poor prognosis. Glioma stem cells (GSCs) are thought to be responsible for the aberrant proliferation and invasion. Targeting the signaling pathways that promote proliferation in GSCs is one of the strategies for glioma treatme...

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Detalhes bibliográficos
Publicado no:Onco Targets Ther
Main Authors: Guo, Yang, Zhang, Peidong, Zhang, Hongtian, Zhang, Peng, Xu, Ruxiang
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5315346/
https://ncbi.nlm.nih.gov/pubmed/28243115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S113390
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