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IDH1-R132H mutation radiosensitizes U87MG glioma cells via epigenetic downregulation of TIGAR
Isocitrate dehydrogenase 1 (IDH1) is the most frequently mutated gene in World Health Organization grade II–III and secondary glioma. The majority of IDH1 mutation cases involve the substitution from arginine to histidine at codon 132 (IDH1-R132H). Although the oncogenic role of IDH1-R132H has been...
Kaydedildi:
| Yayımlandı: | Oncol Lett |
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| Asıl Yazarlar: | , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
D.A. Spandidos
2020
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6956398/ https://ncbi.nlm.nih.gov/pubmed/31966064 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2019.11148 |
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