IDH1(R132H) Mutation Increases U87 Glioma Cell Sensitivity to Radiation Therapy in Hypoxia

Objective. IDH1 codon 132 mutation (mostly Arg132His) is frequently found in gliomas and is associated with longer survival. However, it is still unclear whether IDH1 mutation renders the cell more vulnerable to current treatment, radio- and chemotherapy. Materials and Methods. We transduced U87 wit...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Wang, Xiao-Wei, Labussière, Marianne, Valable, Samuel, Pérès, Elodie A., Guillamo, Jean-Sébastien, Bernaudin, Myriam, Sanson, Marc
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Hindawi Publishing Corporation 2014
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4033346/
https://ncbi.nlm.nih.gov/pubmed/24895549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/198697
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