Silencing erythropoietin receptor on glioma cells reinforces efficacy of temozolomide and X-rays through senescence and mitotic catastrophe

Hypoxia-inducible genes may contribute to therapy resistance in glioblastoma (GBM), the most aggressive and hypoxic brain tumours. It has been recently reported that erythropoietin (EPO) and its receptor (EPOR) are involved in glioma growth. We now investigated whether EPOR signalling may modulate t...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Oncotarget
Main Authors: Pérès, Elodie A., Gérault, Aurélie N., Valable, Samuel, Roussel, Simon, Toutain, Jérôme, Divoux, Didier, Guillamo, Jean-Sébastien, Sanson, Marc, Bernaudin, Myriam, Petit, Edwige
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2014
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4385839/
https://ncbi.nlm.nih.gov/pubmed/25544764
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