Silencing erythropoietin receptor on glioma cells reinforces efficacy of temozolomide and X-rays through senescence and mitotic catastrophe

Hypoxia-inducible genes may contribute to therapy resistance in glioblastoma (GBM), the most aggressive and hypoxic brain tumours. It has been recently reported that erythropoietin (EPO) and its receptor (EPOR) are involved in glioma growth. We now investigated whether EPOR signalling may modulate t...

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Foilsithe in:Oncotarget
Main Authors: Pérès, Elodie A., Gérault, Aurélie N., Valable, Samuel, Roussel, Simon, Toutain, Jérôme, Divoux, Didier, Guillamo, Jean-Sébastien, Sanson, Marc, Bernaudin, Myriam, Petit, Edwige
Formáid: Artigo
Teanga:Inglês
Foilsithe: Impact Journals LLC 2014
Ábhair:
Research Paper
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4385839/
https://ncbi.nlm.nih.gov/pubmed/25544764
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