Hypoxia induces macrophage polarization and re-education toward an M2 phenotype in U87 and U251 glioblastoma models

Hypoxia is a common feature of solid tumors, particularly in glioblastoma (GBM), and known to be a poor prognosis factor in GBM patients. The growth of GBM is also associated with a marked inflammation partially characterized by an accumulation of macrophage (MΦ) of the M2 phenotype. However, the tr...

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Bibliografiske detaljer
Udgivet i:Oncoimmunology
Main Authors: Leblond, Marine M, Gérault, Aurélie N, Corroyer-Dulmont, Aurélien, MacKenzie, Eric T, Petit, Edwige, Bernaudin, Myriam, Valable, Samuel
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2015
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4760330/
https://ncbi.nlm.nih.gov/pubmed/26942063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2015.1056442
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