Carbogen-induced increases in tumor oxygenation depend on the vascular status of the tumor: A multiparametric MRI study in two rat glioblastoma models

The alleviation of hypoxia in glioblastoma with carbogen to improve treatment has met with limited success. Our hypothesis is that the eventual benefits of carbogen depend on the capacity for vasodilation. We examined, with MRI, changes in fractional cerebral blood volume, blood oxygen saturation, a...

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Publicado en:J Cereb Blood Flow Metab
Autores principales: Chakhoyan, Ararat, Corroyer-Dulmont, Aurélien, Leblond, Marine M, Gérault, Aurélie, Toutain, Jérôme, Chazaviel, Laurent, Divoux, Didier, Petit, Edwige, MacKenzie, Eric T, Kauffmann, François, Delcroix, Nicolas, Bernaudin, Myriam, Touzani, Omar, Valable, Samuel
Formato: Artigo
Lenguaje:Inglês
Publicado: SAGE Publications 2016
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Original Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5464716/
https://ncbi.nlm.nih.gov/pubmed/27496553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0271678X16663947
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