Carbogen-induced increases in tumor oxygenation depend on the vascular status of the tumor: A multiparametric MRI study in two rat glioblastoma models

The alleviation of hypoxia in glioblastoma with carbogen to improve treatment has met with limited success. Our hypothesis is that the eventual benefits of carbogen depend on the capacity for vasodilation. We examined, with MRI, changes in fractional cerebral blood volume, blood oxygen saturation, a...

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Detalhes bibliográficos
Publicado no:J Cereb Blood Flow Metab
Main Authors: Chakhoyan, Ararat, Corroyer-Dulmont, Aurélien, Leblond, Marine M, Gérault, Aurélie, Toutain, Jérôme, Chazaviel, Laurent, Divoux, Didier, Petit, Edwige, MacKenzie, Eric T, Kauffmann, François, Delcroix, Nicolas, Bernaudin, Myriam, Touzani, Omar, Valable, Samuel
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2016
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5464716/
https://ncbi.nlm.nih.gov/pubmed/27496553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0271678X16663947
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