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RNAi for contactin 2 inhibits proliferation of U87-glioma stem cells by downregulating AICD, EGFR, and HES1

Glioblastoma is the most common form of malignant brain tumors and has a poor prognosis. Glioma stem cells (GSCs) are thought to be responsible for the aberrant proliferation and invasion. Targeting the signaling pathways that promote proliferation in GSCs is one of the strategies for glioma treatme...

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Publicat a:Onco Targets Ther
Autors principals: Guo, Yang, Zhang, Peidong, Zhang, Hongtian, Zhang, Peng, Xu, Ruxiang
Format: Artigo
Idioma:Inglês
Publicat: Dove Medical Press 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5315346/
https://ncbi.nlm.nih.gov/pubmed/28243115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S113390
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