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DESIGN, SYNTHESIS AND EVALUATION OF ANTIPROLIFERATIVE ACTIVITY OF MELANOMA-TARGETED HISTONE DEACETYLASE INHIBITORS
The clinical validation of histone deacetylase inhibition as a cancer therapeutic modality has stimulated interest in the development of new generation of potent and tumor selective histone deacetylase inhibitors (HDACi). With the goal of selective delivery of the HDACi to melanoma cells, we incorpo...
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| Publicado no: | Bioorg Med Chem Lett |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5314971/ https://ncbi.nlm.nih.gov/pubmed/28131715 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2017.01.044 |
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