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DESIGN, SYNTHESIS AND EVALUATION OF ANTIPROLIFERATIVE ACTIVITY OF MELANOMA-TARGETED HISTONE DEACETYLASE INHIBITORS

The clinical validation of histone deacetylase inhibition as a cancer therapeutic modality has stimulated interest in the development of new generation of potent and tumor selective histone deacetylase inhibitors (HDACi). With the goal of selective delivery of the HDACi to melanoma cells, we incorpo...

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Dades bibliogràfiques
Publicat a:Bioorg Med Chem Lett
Autors principals: Raji, Idris, Ahluwalia, Kabir, Oyelere, Adegboyega K.
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5314971/
https://ncbi.nlm.nih.gov/pubmed/28131715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2017.01.044
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