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Activation of the Mechanistic Target of Rapamycin in SLE: Explosion of Evidence in the Last Five Years

The mechanistic target of rapamycin (mTOR) is a central regulator in cell growth, activation, proliferation, and survival. Activation of the mTOR pathway underlies the pathogenesis of systemic lupus erythematosus (SLE). While mTOR activation and its therapeutic reversal were originally discovered in...

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Dades bibliogràfiques
Publicat a:Curr Rheumatol Rep
Autors principals: Oaks, Zachary, Winans, Thomas, Huang, Nick, Banki, Katalin, Perl, Andras
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5314949/
https://ncbi.nlm.nih.gov/pubmed/27812954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11926-016-0622-8
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