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Understanding the roles of intrinsic disorder in subunits of hemoglobin and the disease process of sickle cell anemia

One of the common genetic disorders is sickle cell anemia, in which 2 recessive alleles must meet to allow for destruction and alteration in the morphology of red blood cells. This usually leads to loss of proper binding of oxygen to hemoglobin and curved, sickle-shaped erythrocytes. The mutation ca...

詳細記述

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書誌詳細
出版年:Intrinsically Disord Proteins
主要な著者: Fitzsimmons, Reis, Amin, Narmin, Uversky, Vladimir N.
フォーマット: Artigo
言語:Inglês
出版事項: Taylor & Francis 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5314875/
https://ncbi.nlm.nih.gov/pubmed/28232898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21690707.2016.1248273
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