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Understanding the roles of intrinsic disorder in subunits of hemoglobin and the disease process of sickle cell anemia

One of the common genetic disorders is sickle cell anemia, in which 2 recessive alleles must meet to allow for destruction and alteration in the morphology of red blood cells. This usually leads to loss of proper binding of oxygen to hemoglobin and curved, sickle-shaped erythrocytes. The mutation ca...

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Podrobná bibliografie
Vydáno v:Intrinsically Disord Proteins
Hlavní autoři: Fitzsimmons, Reis, Amin, Narmin, Uversky, Vladimir N.
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5314875/
https://ncbi.nlm.nih.gov/pubmed/28232898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21690707.2016.1248273
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