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DNA-linked Inhibitor Antibody Assay (DIANA) for sensitive and selective enzyme detection and inhibitor screening

Human diseases are often diagnosed by determining levels of relevant enzymes and treated by enzyme inhibitors. We describe an assay suitable for both ultrasensitive enzyme quantification and quantitative inhibitor screening with unpurified enzymes. In the DNA-linked Inhibitor ANtibody Assay (DIANA),...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Nucleic Acids Res
Päätekijät: Navrátil, Václav, Schimer, Jiří, Tykvart, Jan, Knedlík, Tomáš, Vik, Viktor, Majer, Pavel, Konvalinka, Jan, Šácha, Pavel
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5314793/
https://ncbi.nlm.nih.gov/pubmed/27679479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw853
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