iBodies: Modular Synthetic Antibody Mimetics Based on Hydrophilic Polymers Decorated with Functional Moieties

Antibodies are indispensable tools for biomedicine and anticancer therapy. Nevertheless, their use is compromised by high production costs, limited stability, and difficulty of chemical modification. The design and preparation of synthetic polymer conjugates capable of replacing antibodies in biomed...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Šácha, Pavel, Knedlík, Tomáš, Schimer, Jiří, Tykvart, Jan, Parolek, Jan, Navrátil, Václav, Dvořáková, Petra, Sedlák, František, Ulbrich, Karel, Strohalm, Jiří, Majer, Pavel, Šubr, Vladimír, Konvalinka, Jan
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4755222/
https://ncbi.nlm.nih.gov/pubmed/26749427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201508642
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