Enhancing PET Signal at Target Tissue in Vivo: Dendritic and Multimeric Tris(hydroxypyridinone) Conjugates for Molecular Imaging of α(v)β(3) Integrin Expression with Gallium-68

[Image: see text] Tris(hydroxypyridinone) chelators conjugated to peptides can rapidly complex the positron-emitting isotope gallium-68 ((68)Ga) under mild conditions, and the resulting radiotracers can delineate peptide receptor expression at sites of diseased tissue in vivo. We have synthesized a...

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Detalhes bibliográficos
Publicado no:Bioconjug Chem
Main Authors: Imberti, Cinzia, Terry, Samantha Y. A., Cullinane, Carleen, Clarke, Fiona, Cornish, Georgina H., Ramakrishnan, Nisha K., Roselt, Peter, Cope, Andrew P., Hicks, Rodney J., Blower, Philip J., Ma, Michelle T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2016
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5314429/
https://ncbi.nlm.nih.gov/pubmed/27966893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.bioconjchem.6b00621
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