Manipulating the In Vivo Behaviour of (68)Ga with Tris(Hydroxypyridinone) Chelators: Pretargeting and Blood Clearance

Pretargeting is widely explored in immunoPET as a strategy to reduce radiation exposure of non-target organs and allow the use of short-lived radionuclides that would not otherwise be compatible with the slow pharmacokinetic profiles of antibodies. Here we investigate a pretargeting strategy based o...

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Détails bibliographiques
Publié dans:Int J Mol Sci
Auteurs principaux: Imberti, Cinzia, Adumeau, Pierre, Blower, Julia E., Al Salemee, Fahad, Baguña Torres, Julia, Lewis, Jason S., Zeglis, Brian M., Terry, Samantha Y. A., Blower, Philip J.
Format: Artigo
Langue:Inglês
Publié: MDPI 2020
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7073083/
https://ncbi.nlm.nih.gov/pubmed/32098299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21041496
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