Tuning the properties of tris(hydroxypyridinone) ligands: efficient (68)Ga chelators for PET imaging

The prototype tris(1,6-dimethyl-3-hydroxypyridin-4-one) chelator for gallium-68, THP(Me), has shown great promise for rapid and efficient kit-based (68)Ga labelling of PET radiopharmaceuticals. Peptide derivatives of THP(Me) have been used to image expression of their target receptors in vivo in pre...

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Bibliographische Detailangaben
Veröffentlicht in:Dalton Trans
Hauptverfasser: Imberti, Cinzia, Chen, Yu-Lin, Foley, Calum A., Ma, Michelle T., Paterson, Brett M., Wang, Yifu, Young, Jennifer D., Hider, Robert C., Blower, Philip J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Royal Society of Chemistry 2019
Schlagworte:
Chemistry
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6469224/
https://ncbi.nlm.nih.gov/pubmed/30860215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8dt04454f
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