Endonuclease EEPD1 Is a Gatekeeper for Repair of Stressed Replication Forks

Replication is not as continuous as once thought, with DNA damage frequently stalling replication forks. Aberrant repair of stressed replication forks can result in cell death or genome instability and resulting transformation to malignancy. Stressed replication forks are most commonly repaired via...

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Veröffentlicht in:J Biol Chem
Hauptverfasser: Kim, Hyun-Suk, Nickoloff, Jac A., Wu, Yuehan, Williamson, Elizabeth A., Sidhu, Gurjit Singh, Reinert, Brian L., Jaiswal, Aruna S., Srinivasan, Gayathri, Patel, Bhavita, Kong, Kimi, Burma, Sandeep, Lee, Suk-Hee, Hromas, Robert A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2017
Schlagworte:
DNA and Chromosomes
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5314175/
https://ncbi.nlm.nih.gov/pubmed/28049724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.758235
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