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Endonuclease EEPD1 Is a Gatekeeper for Repair of Stressed Replication Forks

Replication is not as continuous as once thought, with DNA damage frequently stalling replication forks. Aberrant repair of stressed replication forks can result in cell death or genome instability and resulting transformation to malignancy. Stressed replication forks are most commonly repaired via...

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Bibliografske podrobnosti
izdano v:J Biol Chem
Main Authors: Kim, Hyun-Suk, Nickoloff, Jac A., Wu, Yuehan, Williamson, Elizabeth A., Sidhu, Gurjit Singh, Reinert, Brian L., Jaiswal, Aruna S., Srinivasan, Gayathri, Patel, Bhavita, Kong, Kimi, Burma, Sandeep, Lee, Suk-Hee, Hromas, Robert A.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5314175/
https://ncbi.nlm.nih.gov/pubmed/28049724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.758235
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