The homologous recombination component EEPD1 is required for genome stability in response to developmental stress of vertebrate embryogenesis

Stressed replication forks can be conservatively repaired and restarted using homologous recombination (HR), initiated by nuclease cleavage of branched structures at stalled forks. We previously reported that the 5′ nuclease EEPD1 is recruited to stressed replication forks, where it plays critical e...

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Publicat a:Cell Cycle
Autors principals: Chun, Changzoon, Wu, Yuehan, Lee, Suk-Hee, Williamson, Elizabeth A., Reinert, Brian L., Jaiswal, Aruna Shanker, Nickoloff, Jac A., Hromas, Robert A.
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2016
Matèries:
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4889227/
https://ncbi.nlm.nih.gov/pubmed/26900729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2016.1151585
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