Overlapping Specificity of Duplicated Human Pancreatic Elastase 3 Isoforms and Archetypal Porcine Elastase 1 Provides Clues to Evolution of Digestive Enzymes

Chymotrypsin-like elastases (CELAs) are pancreatic serine proteinases that digest dietary proteins. CELAs are typically expressed in multiple isoforms that can vary among different species. The human pancreas does not express CELA1 but secretes two CELA3 isoforms, CELA3A and CELA3B. The reasons for...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Boros, Eszter, Szabó, András, Zboray, Katalin, Héja, Dávid, Pál, Gábor, Sahin-Tóth, Miklós
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Enzymology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5314167/
https://ncbi.nlm.nih.gov/pubmed/28062577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.770560
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