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Overlapping Specificity of Duplicated Human Pancreatic Elastase 3 Isoforms and Archetypal Porcine Elastase 1 Provides Clues to Evolution of Digestive Enzymes

Chymotrypsin-like elastases (CELAs) are pancreatic serine proteinases that digest dietary proteins. CELAs are typically expressed in multiple isoforms that can vary among different species. The human pancreas does not express CELA1 but secretes two CELA3 isoforms, CELA3A and CELA3B. The reasons for...

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Bibliografski detalji
Izdano u:J Biol Chem
Glavni autori: Boros, Eszter, Szabó, András, Zboray, Katalin, Héja, Dávid, Pál, Gábor, Sahin-Tóth, Miklós
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2017
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Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5314167/
https://ncbi.nlm.nih.gov/pubmed/28062577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.770560
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