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Isolation and characterization of a dideoxyguanosine triphosphate-resistant mutant of human immunodeficiency virus reverse transcriptase.

The appearance of drug-resistant strains of viral pathogens is a major difficulty confounding current efforts to block viral infections. The identification and analysis of mutations responsible for drug resistance can provide important clues helpful in understanding the mechanisms of resistance and...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Prasad, V R, Lowy, I, de los Santos, T, Chiang, L, Goff, S P
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC53135/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1722328/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.24.11363
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