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Lysophosphatidic acid signaling through its receptor initiates pro-fibrotic epithelial cell fibroblast communication mediated by epithelial cell derived connective tissue growth factor
The expansion of the fibroblast pool is a critical step in organ fibrosis, but the mechanisms driving expansion remain to be fully clarified. We previously showed that lysophosphatidic acid (LPA) signaling through its receptor LPA(1) expressed on fibroblasts directly induces the recruitment of these...
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| Vydáno v: | Kidney Int |
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| Hlavní autoři: | , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2016
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5313343/ https://ncbi.nlm.nih.gov/pubmed/27927603 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.kint.2016.09.030 |
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