mda-7/IL-24 mediates cancer cell-specific death via regulation of miR-221 and the beclin-1 axis

Melanoma differentiation associated gene-7/Interleukin-24 (mda-7/IL-24) displays broad-spectrum anti-cancer activity in vitro, in vivo in preclinical animal models, and in a phase I/II clinical trial in patients with advanced cancers without harming normal cells or tissues. Here we demonstrate that...

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Pubblicato in:Cancer Res
Autori principali: Pradhan, Anjan K., Talukdar, Sarmistha, Bhoopathi, Praveen, Shen, Xue-Ning, Emdad, Luni, Das, Swadesh K., Sarkar, Devanand, Fisher, Paul B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5313338/
https://ncbi.nlm.nih.gov/pubmed/27940575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-16-1731
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