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Mechanism of internalization of MDA-7/IL-24 protein and its cognate receptors following ligand-receptor docking
Melanoma differentiation associated gene-7 (mda-7/IL-24) is a member of the IL-10 family of cytokines, with ubiquitous direct and “bystander” tumor-selective killing properties. MDA-7/IL-24 protein binds distinct type II cytokine heterodimeric receptor complexes, IL-20R1/IL-20R2, IL-22R1/IL-20R1 and...
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| Izdano u: | Oncotarget |
|---|---|
| Glavni autori: | , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Impact Journals LLC
2019
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6707942/ https://ncbi.nlm.nih.gov/pubmed/31489119 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.27150 |
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