MDA-7/IL-24 regulates the miRNA processing enzyme DICER through downregulation of MITF

Melanoma differentiation-associated gene-7/interleukin-24 (mda-7/IL-24) is a multifunctional cytokine displaying broad-spectrum anticancer activity in vitro or in vivo in preclinical animal cancer models and in a phase 1/2 clinical trial in patients with advanced cancers. mda-7/IL-24 targets specifi...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Pradhan, Anjan K., Bhoopathi, Praveen, Talukdar, Sarmistha, Scheunemann, Danielle, Sarkar, Devanand, Cavenee, Webster K., Das, Swadesh K., Emdad, Luni, Fisher, Paul B.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6431152/
https://ncbi.nlm.nih.gov/pubmed/30842276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1819869116
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