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Fibronectin signals through integrin α5β1 to regulate cardiovascular development in a cell type-specific manner

Fibronectin (Fn1) is an evolutionarily conserved extracellular matrix glycoprotein essential for embryonic development. Global deletion of Fn1 leads to mid-gestation lethality from cardiovascular defects. However, severe morphogenetic defects that occur early in embryogenesis in these embryos preclu...

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Bibliografski detalji
Izdano u:Dev Biol
Glavni autori: Chen, Dongying, Wang, Xia, Liang, Dong, Gordon, Julie, Mittal, Ashok, Manley, Nancy, Degenhardt, Karl, Astrof, Sophie
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5312697/
https://ncbi.nlm.nih.gov/pubmed/26434918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2015.09.016
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