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Mesodermal expression of integrin α5β1 regulates neural crest development and cardiovascular morphogenesis

Integrin α5-null embryos die in mid-gestation from severe defects in cardiovascular morphogenesis, which stem from defective development of the neural crest, heart and vasculature. To investigate the role of integrin α5β1 in cardiovascular development, we used the Mesp1(Cre) knock-in strain of mice...

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Detalhes bibliográficos
Publicado no:Dev Biol
Main Authors: Liang, Dong, Wang, Xia, Mittal, Ashok, Dhiman, Sonam, Hou, Shuan-Yu, Degenhardt, Karl, Astrof, Sophie
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4252364/
https://ncbi.nlm.nih.gov/pubmed/25242040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2014.09.014
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