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Mesodermal expression of integrin α5β1 regulates neural crest development and cardiovascular morphogenesis

Integrin α5-null embryos die in mid-gestation from severe defects in cardiovascular morphogenesis, which stem from defective development of the neural crest, heart and vasculature. To investigate the role of integrin α5β1 in cardiovascular development, we used the Mesp1(Cre) knock-in strain of mice...

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Bibliografiske detaljer
Udgivet i:Dev Biol
Main Authors: Liang, Dong, Wang, Xia, Mittal, Ashok, Dhiman, Sonam, Hou, Shuan-Yu, Degenhardt, Karl, Astrof, Sophie
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4252364/
https://ncbi.nlm.nih.gov/pubmed/25242040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2014.09.014
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