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Fibronectin signals through integrin α5β1 to regulate cardiovascular development in a cell type-specific manner
Fibronectin (Fn1) is an evolutionarily conserved extracellular matrix glycoprotein essential for embryonic development. Global deletion of Fn1 leads to mid-gestation lethality from cardiovascular defects. However, severe morphogenetic defects that occur early in embryogenesis in these embryos preclu...
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| Publicado no: | Dev Biol |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5312697/ https://ncbi.nlm.nih.gov/pubmed/26434918 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2015.09.016 |
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