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AICAR Positively Regulate Glycogen Synthase Activity and LDL Receptor Expression through Raf-1/MEK/p42/44(MAPK)/p90(RSK)/GSK-3 Signaling Cascade
5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside (AICAR) is a commonly used pharmacological agent to study physiological effects which are similar to those of exercise. However, signal transduction pathways by which AICAR elicits downstream effects in liver are poorly understood. We report here t...
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| Publicado no: | Biochem Pharmacol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5312663/ https://ncbi.nlm.nih.gov/pubmed/17945190 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2007.08.028 |
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