CALHM1 controls the Ca(2+)-dependent MEK, ERK, RSK and MSK signaling cascade in neurons

Calcium homeostasis modulator 1 (CALHM1) is a Ca(2+) channel controlling neuronal excitability and potentially involved in the pathogenesis of Alzheimer's disease (AD). Although strong evidence indicates that CALHM1 is required for neuronal electrical activity, its role in intracellular Ca(2+)...

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Udgivet i:J Cell Sci
Main Authors: Dreses-Werringloer, Ute, Vingtdeux, Valérie, Zhao, Haitian, Chandakkar, Pallavi, Davies, Peter, Marambaud, Philippe
Format: Artigo
Sprog:Inglês
Udgivet: The Company of Biologists 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4481642/
https://ncbi.nlm.nih.gov/pubmed/23345406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.117135
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