CALHM1 controls the Ca(2+)-dependent MEK, ERK, RSK and MSK signaling cascade in neurons

Calcium homeostasis modulator 1 (CALHM1) is a Ca(2+) channel controlling neuronal excitability and potentially involved in the pathogenesis of Alzheimer's disease (AD). Although strong evidence indicates that CALHM1 is required for neuronal electrical activity, its role in intracellular Ca(2+)...

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Veröffentlicht in:J Cell Sci
Hauptverfasser: Dreses-Werringloer, Ute, Vingtdeux, Valérie, Zhao, Haitian, Chandakkar, Pallavi, Davies, Peter, Marambaud, Philippe
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Company of Biologists 2013
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4481642/
https://ncbi.nlm.nih.gov/pubmed/23345406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.117135
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