Effect of the CALHM1 G330D and R154H Human Variants on the Control of Cytosolic Ca(2+) and Aβ Levels

CALHM1 is a plasma membrane voltage-gated Ca(2+)-permeable ion channel that controls amyloid-β (Aβ) metabolism and is potentially involved in the onset of Alzheimer's disease (AD). Recently, Rubio-Moscardo et al. (PLoS One (2013) 8: e74203) reported the identification of two CALHM1 variants, G3...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Vingtdeux, Valérie, Tanis, Jessica E., Chandakkar, Pallavi, Zhao, Haitian, Dreses-Werringloer, Ute, Campagne, Fabien, Foskett, J. Kevin, Marambaud, Philippe
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2014
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4227689/
https://ncbi.nlm.nih.gov/pubmed/25386646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0112484
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