A polymorphism in CALHM1 influences Ca(2+) homeostasis, Aβlevels, and Alzheimer’s disease risk

Alzheimer’s disease (AD) is a genetically heterogeneous disorder characterized by early hippocampal atrophy and cerebral Aβ peptide deposition. Using TissueInfo to screen for genes preferentially expressed in the hippocampus and located in AD linkage regions, we identified a novel gene on 10q24.33 t...

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Hoofdauteurs: Dreses-Werringloer, Ute, Lambert, Jean-Charles, Vingtdeux, Valérie, Zhao, Haitian, Vais, Horia, Siebert, Adam, Jain, Ankit, Koppel, Jeremy, Rovelet-Lecrux, Anne, Hannequin, Didier, Pasquier, Florence, Galimberti, Daniela, Scarpini, Elio, Mann, David, Lendon, Corinne, Campion, Dominique, Amouyel, Philippe, Davies, Peter, Foskett, J. Kevin, Campagne, Fabien, Marambaud, Philippe
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2008
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2577842/
https://ncbi.nlm.nih.gov/pubmed/18585350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2008.05.048
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