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hERG1/Kv11.1 activation stimulates transcription of p21(waf/cip) in breast cancer cells via a calcineurin-dependent mechanism

The function of Kv11.1 is emerging in breast cancer biology, as a growing body of evidence indicates that the hERG1/Kv11.1 potassium channel is aberrantly expressed in several cancer types including breast cancers. The biological effects of Kv11.1 channel blockers and their associated side effects a...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Perez-Neut, Mathew, Rao, Vidhya R., Gentile, Saverio
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5312283/
https://ncbi.nlm.nih.gov/pubmed/25945833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.3797
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