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Activation of hERG3 channel stimulates autophagy and promotes cellular senescence in melanoma
Ion channels play a major factor in maintaining cellular homeostasis but very little is known about the role of these proteins in cancer biology. In this work we have discovered that, the Kv11.3 (hERG3) a plasma-membrane potassium channel plays a critical role in the regulation of autophagy in a can...
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| Publicat a: | Oncotarget |
|---|---|
| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Impact Journals LLC
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5008339/ https://ncbi.nlm.nih.gov/pubmed/26942884 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7831 |
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