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Activation of hERG3 channel stimulates autophagy and promotes cellular senescence in melanoma
Ion channels play a major factor in maintaining cellular homeostasis but very little is known about the role of these proteins in cancer biology. In this work we have discovered that, the Kv11.3 (hERG3) a plasma-membrane potassium channel plays a critical role in the regulation of autophagy in a can...
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Publicado no: | Oncotarget |
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Main Authors: | , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Impact Journals LLC
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5008339/ https://ncbi.nlm.nih.gov/pubmed/26942884 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7831 |
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