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Functional characterization of Kv11.1 (hERG) potassium channels split in the voltage-sensing domain

Voltage-dependent KCNH family potassium channel functionality can be reconstructed using non-covalently linked voltage-sensing domain (VSD) and pore modules (split channels). However, the necessity of a covalent continuity for channel function has not been evaluated at other points within the two fu...

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Détails bibliographiques
Publié dans:Pflugers Arch
Auteurs principaux: de la Peña, Pilar, Domínguez, Pedro, Barros, Francisco
Format: Artigo
Langue:Inglês
Publié: Springer Berlin Heidelberg 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6013512/
https://ncbi.nlm.nih.gov/pubmed/29572566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00424-018-2135-y
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