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PDCD4 is a CSL associated protein with a transcription repressive function in cancer associated fibroblast activation
The Notch/CSL pathway plays an important role in skin homeostasis and carcinogenesis. CSL, the key effector of canonical Notch signaling endowed with an intrinsic transcription repressive function, suppresses stromal fibroblast senescence and Cancer Associated Fibroblast (CAF) activation through dir...
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| Publié dans: | Oncotarget |
|---|---|
| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Impact Journals LLC
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5312270/ https://ncbi.nlm.nih.gov/pubmed/27542230 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11227 |
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