PDCD4 is a CSL associated protein with a transcription repressive function in cancer associated fibroblast activation

The Notch/CSL pathway plays an important role in skin homeostasis and carcinogenesis. CSL, the key effector of canonical Notch signaling endowed with an intrinsic transcription repressive function, suppresses stromal fibroblast senescence and Cancer Associated Fibroblast (CAF) activation through dir...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Jo, Seung-Hee, Kim, Dong Eun, Clocchiatti, Andrea, Dotto, G. Paolo
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2016
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Priority Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5312270/
https://ncbi.nlm.nih.gov/pubmed/27542230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11227
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