PDCD4 is a CSL associated protein with a transcription repressive function in cancer associated fibroblast activation

The Notch/CSL pathway plays an important role in skin homeostasis and carcinogenesis. CSL, the key effector of canonical Notch signaling endowed with an intrinsic transcription repressive function, suppresses stromal fibroblast senescence and Cancer Associated Fibroblast (CAF) activation through dir...

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Vydáno v:Oncotarget
Hlavní autoři: Jo, Seung-Hee, Kim, Dong Eun, Clocchiatti, Andrea, Dotto, G. Paolo
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2016
Témata:
Priority Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5312270/
https://ncbi.nlm.nih.gov/pubmed/27542230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11227
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