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S. cerevisiae Trm140 has two recognition modes for 3-methylcytidine modification of the anticodon loop of tRNA substrates

The 3-methylcytidine (m(3)C) modification is ubiquitous in eukaryotic tRNA, widely found at C(32) in the anticodon loop of tRNA(Thr), tRNA(Ser), and some tRNA(Arg) species, as well as in the variable loop (V-loop) of certain tRNA(Ser) species. In the yeast Saccharomyces cerevisiae, formation of m(3)...

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Détails bibliographiques
Publié dans:RNA
Auteurs principaux: Han, Lu, Marcus, Erin, D'Silva, Sonia, Phizicky, Eric M.
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory Press 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5311504/
https://ncbi.nlm.nih.gov/pubmed/28003514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.059667.116
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