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Yeast Trm7 interacts with distinct proteins for critical modifications of the tRNA(Phe) anticodon loop

Post-transcriptional modification of the tRNA anticodon loop is critical for translation. Yeast Trm7 is required for 2′-O-methylation of C(32) and N(34) of tRNA(Phe), tRNA(Trp), and tRNA(Leu(UAA)) to form Cm(32) and Nm(34), and trm7-Δ mutants have severe growth and translation defects, but the reaso...

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Detalhes bibliográficos
Main Authors: Guy, Michael P., Podyma, Brandon M., Preston, Melanie A., Shaheen, Hussam H., Krivos, Kady L., Limbach, Patrick A., Hopper, Anita K., Phizicky, Eric M.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3446714/
https://ncbi.nlm.nih.gov/pubmed/22912484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.035287.112
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