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S. cerevisiae Trm140 has two recognition modes for 3-methylcytidine modification of the anticodon loop of tRNA substrates

The 3-methylcytidine (m(3)C) modification is ubiquitous in eukaryotic tRNA, widely found at C(32) in the anticodon loop of tRNA(Thr), tRNA(Ser), and some tRNA(Arg) species, as well as in the variable loop (V-loop) of certain tRNA(Ser) species. In the yeast Saccharomyces cerevisiae, formation of m(3)...

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Detalles Bibliográficos
Publicado en:RNA
Main Authors: Han, Lu, Marcus, Erin, D'Silva, Sonia, Phizicky, Eric M.
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5311504/
https://ncbi.nlm.nih.gov/pubmed/28003514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.059667.116
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