Adenovirus Serotype 5 Vaccination Results in Suboptimal CD4 T Helper 1 Responses in Mice

Adenovirus serotype 5 (Ad5) is one of the most widely used viral vectors and is known to generate potent T cell responses. While many previous studies have characterized Ad5-induced CD8 T cell responses, there is a relative lack of detailed studies that have analyzed CD4 T cells elicited by Ad5 vacc...

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Dettagli Bibliografici
Pubblicato in:J Virol
Autori principali: Lee, Junghwa, Hashimoto, Masao, Im, Se Jin, Araki, Koichi, Jin, Hyun-Tak, Davis, Carl W., Konieczny, Bogumila T., Spies, Gregory A., McElrath, M. Juliana, Ahmed, Rafi
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2017
Soggetti:
Pathogenesis and Immunity
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5309930/
https://ncbi.nlm.nih.gov/pubmed/28003483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01132-16
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