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PD-1+ stemlike CD8 T cells are resident in lymphoid tissues during persistent LCMV infection

The migratory patterns of virus-specific CD8 T cells during chronic viral infection are not well understood. To address this issue, we have done parabiosis experiments during chronic lymphocytic choriomeningitis virus (LCMV) infection of mice. We found that despite the high frequency of virus-specif...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Im, Se Jin, Konieczny, Bogumila T, Hudson, William H., Masopust, David, Ahmed, Rafi
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7049149/
https://ncbi.nlm.nih.gov/pubmed/32034098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1917298117
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