CRISPR–Cas9-targeted fragmentation and selective sequencing enable massively parallel microsatellite analysis

Microsatellites are multi-allelic and composed of short tandem repeats (STRs) with individual motifs composed of mononucleotides, dinucleotides or higher including hexamers. Next-generation sequencing approaches and other STR assays rely on a limited number of PCR amplicons, typically in the tens. H...

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Bibliographic Details
Published in:Nat Commun
Main Authors: Shin, GiWon, Grimes, Susan M., Lee, HoJoon, Lau, Billy T., Xia, Li C., Ji, Hanlee P.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2017
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5309709/
https://ncbi.nlm.nih.gov/pubmed/28169275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms14291
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