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Impact of vesicular glutamate leakage on synaptic transmission at the calyx of Held

KEY POINTS: It is controversial whether glutamate can leak out of vesicles in the nerve terminal. To address this issue, we abolished vesicular glutamate uptake by washing out presynaptic cytosolic glutamate or by blocking vacuolar ATPase activity using bafilomycin A1. In the absence of vesicular gl...

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Détails bibliographiques
Publié dans:J Physiol
Auteurs principaux: Takami, Chihiro, Eguchi, Kohgaku, Hori, Tetsuya, Takahashi, Tomoyuki
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5309358/
https://ncbi.nlm.nih.gov/pubmed/27801501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP273467
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