Wild-Type Monomeric α-Synuclein Can Impair Vesicle Endocytosis and Synaptic Fidelity via Tubulin Polymerization at the Calyx of Held

α-Synuclein is a presynaptic protein the function of which has yet to be identified, but its neuronal content increases in patients of synucleinopathies including Parkinson's disease. Chronic overexpression of α-synuclein reportedly expresses various phenotypes of synaptic dysfunction, but the...

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Vydáno v:J Neurosci
Hlavní autoři: Eguchi, Kohgaku, Taoufiq, Zacharie, Thorn-Seshold, Oliver, Trauner, Dirk, Hasegawa, Masato, Takahashi, Tomoyuki
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2017
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Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6596501/
https://ncbi.nlm.nih.gov/pubmed/28576942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0179-17.2017
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