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Impact of vesicular glutamate leakage on synaptic transmission at the calyx of Held

KEY POINTS: It is controversial whether glutamate can leak out of vesicles in the nerve terminal. To address this issue, we abolished vesicular glutamate uptake by washing out presynaptic cytosolic glutamate or by blocking vacuolar ATPase activity using bafilomycin A1. In the absence of vesicular gl...

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Detalhes bibliográficos
Publicado no:J Physiol
Main Authors: Takami, Chihiro, Eguchi, Kohgaku, Hori, Tetsuya, Takahashi, Tomoyuki
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5309358/
https://ncbi.nlm.nih.gov/pubmed/27801501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP273467
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